Pharmacodynamic Approach for Ceftazidime Treatment of AECB (II)

Median MIC of pathogens - 1.65 (range: 0.05 - 8 mg/l)

Median serum maximum concen-tration during continuous infusion - 48 (range: 30 - 139 mg/l)

Median serum trough concentration during continuous infusion - 13.9 (range: 5.2 - 43 mg/l)

Median AUC/24 hrduring continuous infusion - 836 (range: 438 - 1838 mg*h/l)

Median AUC/24 hrwith intermittent infusion - 1066 (range: 812 - 1502 mg*h/l)

AUC/MiC ratioduring continuous infusion - 105 (MIC: 8 mg/l)

PD-Results:

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