Time above MICCorrelation of serum pharmacokinetics with MIC (susceptibility) of an organism

Time

Antibacterial concentration (µg/ml)

2

Drug A

Drug B

Drug A present at concentration of 2 µg/ml for 50% of dosing interval

Drug B present at concentration of 2 µg/ml for 30% of dosing interval

4

6

8

0

MIC

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